Conserved boundary elements from the Hox complex of mosquito, Anopheles gambiae
نویسندگان
چکیده
منابع مشابه
Conserved boundary elements from the Hox complex of mosquito, Anopheles gambiae
The conservation of hox genes as well as their genomic organization across the phyla suggests that this system of anterior-posterior axis formation arose early during evolution and has come under strong selection pressure. Studies in the split Hox cluster of Drosophila have shown that proper expression of hox genes is dependent on chromatin domain boundaries that prevent inappropriate interacti...
متن کاملThe genome sequence of the malaria mosquito Anopheles gambiae.
Anopheles gambiae is the principal vector of malaria, a disease that afflicts more than 500 million people and causes more than 1 million deaths each year. Tenfold shotgun sequence coverage was obtained from the PEST strain of A. gambiae and assembled into scaffolds that span 278 million base pairs. A total of 91% of the genome was organized in 303 scaffolds; the largest scaffold was 23.1 milli...
متن کاملOrganization of olfactory centres in the malaria mosquito Anopheles gambiae
Mosquitoes are vectors for multiple infectious human diseases and use a variety of sensory cues (olfactory, temperature, humidity and visual) to locate a human host. A comprehensive understanding of the circuitry underlying sensory signalling in the mosquito brain is lacking. Here we used the Q-system of binary gene expression to develop transgenic lines of Anopheles gambiae in which olfactory ...
متن کاملMicroRNA Tissue Atlas of the Malaria Mosquito Anopheles gambiae
Anopheles gambiae mosquitoes transmit the human malaria parasite Plasmodium falciparum, which causes the majority of fatal malaria cases worldwide. The hematophagous lifestyle defines mosquito reproductive biology and is exploited by P. falciparum for its own sexual reproduction and transmission. The two main phases of the mosquito reproductive cycle, previtellogenic (PV) and postblood meal (PB...
متن کاملFemale-biased gene expression in the malaria mosquito Anopheles gambiae
Females of the malaria-carrying mosquito, Anopheles gambiae, must deal with a number of tasks never confronted by males, including blood-feeding and defense against Plasmodium infection. Here, we examine global gene expression differences between the sexes in A. gambiae via Affymetrix GeneChip® microarrays and find a dramatic over-representation of genes expressed more highly in females. Approx...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2012
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gks1178